Question 1

Which of the following proteins is a phosphatase activated by Ca2+ essential for T cell proliferation?

Accepted Answer

A)  calcineurin
B)  calmodulin (CaM) 
C)  rhodopsin
D)  RasGAP
E)  MAPKF) B) and D)
G) B) and C)

Question 2

Matching
-The first G protein-coupled receptor (GPCR) to be structurally analyzed at the atomic level was _____.

Accepted Answer

A)  receptors
B)  phosphoinositide
C)  rhodopsin
D)  calmodulin
E)  insulinF) hypothalamusG) cortisolH) adrenal cortexI) cyclic AMPJ) RasGAPK) islets of LangerhansL) adenylate cyclase (A
C)  M) receptor tyrosine kinase (RTK) N) B) and J)
O) D) and M)

Question 3

The insulin signaling pathway includes which of the following steps?

Accepted Answer

A)  ligand-induced dimerization of the receptor and phosphorylation of IRS-1 and/or IRS-2 proteins
B)  autophosphorylation and phosphorylation of IRS-1 and/or IRS-2 proteins
C)  IRS-1-induced dimerization of the receptor, autophosphorylation, and phosphorylation of SH2 domains
D)  autophosphorylation and dephosphorylation of IRS-1 and/or SH2 domains
E)  none of the aboveF) C) and E)
G) A) and B)

Question 4

Based on the following figure, which of the following are possible?  I."A" could be adenylate cyclase.
II."B" is a receptor protein.
III."C" could be an inactive Ras protein.
IV."D" could be an SH2 domain.

Accepted Answer

A)  I, II, III, IV
B)  I, II, III
C)  II, III, IV
D)  I only
E)  III onlyF) A) and E)
G) B) and E)

Question 5

The ability of receptors to adapt to long-term stimulation by responding to changes in stimulation levels rather than absolute values of stimulation is called

Accepted Answer

A)  dual-specificity.
B)  intrasteric sensitivity.
C)  autoinhibition.
D)  desensitization.
E)  switch regional detection.F) B) and E)
G) A) and C)

Question 6

Matching
-The ____ signaling pathway relies on GTP dependent hydrolysis for subsequent synthesis of cAMP.

Accepted Answer

A)  receptors
B)  phosphoinositide
C)  rhodopsin
D)  calmodulin
E)  insulinF) hypothalamusG) cortisolH) adrenal cortexI) cyclic AMPJ) RasGAPK) islets of LangerhansL) adenylate cyclase (A
C)  M) receptor tyrosine kinase (RTK) N) G) and I)
O) A) and H)

Question 7

Matching
-The gland that is predominately responsible for producing the hormone that is released in response to consumption of a meal particularly high in carbohydrates.

Accepted Answer

A)  receptors
B)  phosphoinositide
C)  rhodopsin
D)  calmodulin
E)  insulinF) hypothalamusG) cortisolH) adrenal cortexI) cyclic AMPJ) RasGAPK) islets of LangerhansL) adenylate cyclase (A
C)  M) receptor tyrosine kinase (RTK) N) A) and I)
O) B) and G)

Question 8

Matching
-Proteins that bind molecules and elicit a cellular response are called _____.

Accepted Answer

A)  receptors
B)  phosphoinositide
C)  rhodopsin
D)  calmodulin
E)  insulinF) hypothalamusG) cortisolH) adrenal cortexI) cyclic AMPJ) RasGAPK) islets of LangerhansL) adenylate cyclase (A
C)  M) receptor tyrosine kinase (RTK) N) I) and J)
O) B) and E)

Question 9

Which of the following describes the similarity between the following words? DAG, cAMP, IP3

Accepted Answer

A)  All of them induce conformational changes in PKA.
B)  All of them activate adenylate cyclase.
C)  All of them require phosphorylation in order to function.
D)  All of them function as second messengers.
E)  All them result from the activity of phosphoprotein lipase.F) A) and D)
G) A) and E)

Question 10

Matching
-The hormone _____ is responsible for a variety of actions including the ability to cope with stress.

Accepted Answer

A)  receptors
B)  phosphoinositide
C)  rhodopsin
D)  calmodulin
E)  insulinF) hypothalamusG) cortisolH) adrenal cortexI) cyclic AMPJ) RasGAPK) islets of LangerhansL) adenylate cyclase (A
C)  M) receptor tyrosine kinase (RTK) N) B) and I)
O) E) and F)

Exam 13: Biochemical Signaling

Matching -The first G protein-coupled receptor (GPCR) to be structurally analyzed at the atomic level was _____.

Correct Answer
verified

The insulin signaling pathway includes which of the following steps?

Correct Answer
verified

The ability of receptors to adapt to long-term stimulation by responding to changes in stimulation levels rather than absolute values of stimulation is called

Correct Answer
verified

Which of the following proteins is a phosphatase activated by Ca²⁺ essential for T cell proliferation?

Correct Answer
verified

Matching -The hormone _____ is responsible for a variety of actions including the ability to cope with stress.

Correct Answer
verified

Matching -The ____ signaling pathway relies on GTP dependent hydrolysis for subsequent synthesis of cAMP.

Correct Answer
verified

Which of the following describes the similarity between the following words? DAG, cAMP, IP3

Correct Answer
verified

Matching -Proteins that bind molecules and elicit a cellular response are called _____.

Correct Answer
verified

Matching -The gland that is predominately responsible for producing the hormone that is released in response to consumption of a meal particularly high in carbohydrates.

Correct Answer
verified

Based on the following figure, which of the following are possible? I."A" could be adenylate cyclase. II."B" is a receptor protein. III."C" could be an inactive Ras protein. IV."D" could be an SH2 domain.

Correct Answer
verified

Exam 13: Biochemical Signaling

Matching -The first G protein-coupled receptor (GPCR) to be structurally analyzed at the atomic level was _____.

Correct AnswerverifiedShow Answer

The insulin signaling pathway includes which of the following steps?

Correct AnswerverifiedShow Answer

The ability of receptors to adapt to long-term stimulation by responding to changes in stimulation levels rather than absolute values of stimulation is called

Correct AnswerverifiedShow Answer

Which of the following proteins is a phosphatase activated by Ca2+ essential for T cell proliferation?

Correct AnswerverifiedShow Answer

Matching -The hormone _____ is responsible for a variety of actions including the ability to cope with stress.

Correct AnswerverifiedShow Answer

Matching -The ____ signaling pathway relies on GTP dependent hydrolysis for subsequent synthesis of cAMP.

Correct AnswerverifiedShow Answer

Which of the following describes the similarity between the following words? DAG, cAMP, IP3

Correct AnswerverifiedShow Answer

Matching -Proteins that bind molecules and elicit a cellular response are called _____.

Correct AnswerverifiedShow Answer

Matching -The gland that is predominately responsible for producing the hormone that is released in response to consumption of a meal particularly high in carbohydrates.

Correct AnswerverifiedShow Answer

Based on the following figure, which of the following are possible? I."A" could be adenylate cyclase. II."B" is a receptor protein. III."C" could be an inactive Ras protein. IV."D" could be an SH2 domain.

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Which of the following proteins is a phosphatase activated by Ca²⁺ essential for T cell proliferation?

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified