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In clinical estimates, ________ of total body water is in the ICF and ________ in the ECF.


A) one-tenth; nine-tenths
B) one-quarter; three-quarters
C) one-half; one-half
D) two-thirds; one-third
E) one-third; two-thirds

F) A) and E)
G) B) and E)

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Which of the following descriptions best fits the acid-base disorder respiratory acidosis?


A) consequence of hyperventilation (for example, in fever or mental illness)
B) consequence of prolonged vomiting
C) consequence of reduced alveolar ventilation (for example, due to emphysema)
D) consequence of tissue hypoxia (for example, in ischemic conditions)
E) consequence of strenuous exercise

F) A) and B)
G) A) and D)

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The most dangerous problems with electrolyte balance are caused by an imbalance between gains and lossesof


A) calcium ions.
B) chlorine ions.
C) potassium ions.
D) sodium ions.
E) electrons.

F) A) and B)
G) C) and D)

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The release of atrial naturetic peptides from the heart will cause the body to


A) conserve sodium ions.
B) decrease ECF.
C) excrete potassium ions.
D) conserve sodium ions and decrease ECF.
E) excrete sodium ions and decrease ECF.

F) C) and D)
G) A) and B)

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________ promotes water reabsorption at the kidneys and stimulates thirst.


A) ADH
B) Aldosterone
C) Calcitonin
D) Renin
E) Natriuretic peptide

F) None of the above
G) All of the above

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To reduce brain swelling by pulling water out of brain cells, a substance can be injected intravenouslytoincrease the osmotic pressure of interstitial fluid. Which of the following properties must this substance lack in order to be effective?


A) permeable to capillary endothelium
B) nontoxic to neurons
C) permeable to brain plasma membranes
D) impermeable to brain plasma membranes
E) soluble in water

F) A) and C)
G) A) and B)

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Water molecules move across cells by


A) osmosis.
B) primary active transport.
C) secondary active transport.
D) activity of the sodium-potassium pump.
E) phagocytosis.

F) A) and C)
G) All of the above

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Aldosterone


A) is secreted in response to decreased levels of potassium in the blood.
B) promotes sodium retention in the kidneys.
C) helps decrease blood volume and lower blood pressure.
D) regulates blood calcium levels.
E) regulates water reabsorption in the kidneys.

F) A) and B)
G) None of the above

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Hypoventilation leads to


A) respiratory acidosis.
B) respiratory alkalosis.
C) metabolic acidosis.
D) metabolic alkalosis.
E) lactic acidosis.

F) A) and B)
G) None of the above

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Which hormone most affects the osmolarity of blood?


A) ADH
B) angiotensin II
C) PTH
D) ANP
E) epinephrine

F) A) and E)
G) B) and D)

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When the pH ________, a state of acidosis exists.


A) rises above 7
B) falls below 7
C) falls below 6.5
D) falls below 7.35
E) rises above 7.5

F) A) and D)
G) B) and E)

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In-Text Figure Based Questions -In which body fluid do the phosphate and protein buffer systems help regulate the pH? (Figure 27-10)


A) intracellular fluid
B) extracellular fluid
C) blood plasma
D) cerebrospinal fluid

E) A) and D)
F) B) and D)

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In a lean adult male, the body consists of about ________ percent water.


A) 60
B) 90
C) 40
D) 10
E) 80

F) B) and E)
G) A) and D)

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The typical value of water losses and gains each day is


A) 500 mL.
B) 1000 mL.
C) 1500 mL.
D) 2000 mL.
E) 2500 mL.

F) None of the above
G) B) and D)

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Severe kidney damage, such as glomerulonephritis, often leads to


A) acute respiratory acidosis.
B) respiratory alkalosis.
C) metabolic acidosis.
D) metabolic alkalosis.
E) chronic respiratory acidosis.

F) C) and D)
G) B) and E)

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Administration of a medication in the elderly can result in a much higher dosage than the clinician might intend because


A) the metabolic rate in the elderly is so high.
B) the kidneys of the elderly do not work well.
C) the elderly have less water content in the body.
D) other medications they take might enhance the concentration of another drug.
E) they cannot regulate pH well.

F) A) and D)
G) B) and E)

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Excess hydrogen ion is eliminated from the body largely by


A) sweating.
B) the kidneys.
C) the liver.
D) the feces.
E) buffers.

F) B) and C)
G) A) and B)

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The two major subdivisions of the ECF are the


A) ICF and plasma.
B) interstitial fluid and plasma.
C) lymph and plasma.
D) serous fluids and lymph.
E) interstitial fluid and CSF.

F) B) and D)
G) C) and E)

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The maintenance of normal volume and composition of extracellular and intracellular fluids is vital to life.List and briefly describe the kinds of homeostasis involved.

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Three types of homeostasis are involved:...

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Which of the following statements is false regarding fluid and electrolyte balance?


A) Fluctuations in diet will affect babies less because they have so much water content.
B) Older people tend to become more dehydrated.
C) Kidney functions tend to decrease as one ages.
D) Aging correlates with problems in various organ systems, which can enhance acid-base imbalance problems.
E) A fetus obtains water and electrolytes from the maternal bloodstream.

F) A) and D)
G) A) and C)

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