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The gene that codes for a protein capable of repressing an operon is called the ________.


A) operator
B) structural locus
C) regulator
D) promoter
E) terminator

F) C) and E)
G) A) and E)

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Which of the following is not true of transposons?


A) Can change pigmentation
B) Can replace damaged DNA
C) Can transfer drug resistance
D) Can change the genome
E) Are always part of plasmids

F) C) and D)
G) A) and E)

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Semiconservative replication refers to ________.


A) each base bonding at the 1' position of the sugar
B) a purine always bonding to a pyrimidine
C) one helix strand that runs from the 5' to 3' direction and the other strand runs from the 3' to 5' direction
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule
E) None of the choices are correct.

F) A) and E)
G) A) and C)

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Three consecutive bases in the DNA of a gene represent the code for one ________.


A) protein
B) nucleotide
C) amino acid
D) purine
E) pyrimidine

F) D) and E)
G) B) and C)

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All of the following pertain to transcription except ________.


A) occurs on a ribosome in the cytoplasm
B) occurs before translation
C) requires RNA polymerase
D) requires a template DNA strand
E) proceeds in the 5' to 3' direction of the growing mRNA molecule

F) All of the above
G) A) and E)

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The discovery of single nucleotide polymorphisms in the human genome means that ________.


A) individual risk for specific diseases can be analyzed,and personalized medicine designed as a result of the analysis
B) the human species is in grave danger of dying out due to the threat of mutation across the species
C) genes are not important in determining the individual phenotypes of individuals,since we are all similar in our growth,metabolism and reproduction
D) mutations are far more dangerous than we thought,prior to the Human Genome Project

E) C) and D)
F) None of the above

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The nontranscribed region of DNA to which RNA polymerase binds to initiate transcription is called the ________.


A) promoter
B) operator
C) operon
D) exon
E) intron

F) None of the above
G) A) and B)

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Restriction endonucleases recognize and clip at DNA base sequences called ________.


A) codons
B) palindromes
C) introns
D) exons
E) genes

F) A) and D)
G) None of the above

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An 18-month-old male is admitted to the hospital with symptoms of a respiratory infection. The patient's mother reports that since birth, the toddler has frequently had a cough and copious nasal secretions. His weight gain has been poor, despite his excellent appetite. The patient appears in moderate respiratory distress, so oxygen therapy and intravenous fluids are initiated. The physician orders tests for cystic fibrosis due to the patient's history and clinical presentation. When the tests confirm the diagnosis, as the RN, you provide education to the mother regarding this autosomal recessive disease. -The RN is aware that many different types of mutations have been identified in the gene that causes cystic fibrosis.Which of the following terms would best describe a mutation that leads to the deletion of two bases from a DNA sequence?


A) Frameshift mutation
B) Back mutation
C) Silent mutation
D) Point mutation

E) C) and D)
F) B) and D)

Correct Answer

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Synthetic biology is an emerging field of science whereby researchers are creating new molecules and organisms from an array of chemicals,rather than as a result of cellular reproduction.

A) True
B) False

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The following pertain to ribosomes during protein synthesis except ________.


A) they participate in both transcription and translation
B) they participate only in translation
C) they scans the mRNA for an AUG codon
D) they are composed of ribosomal RNA and protein
E) they shift to the right along the mRNA strand from one codon to the next

F) All of the above
G) B) and E)

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Full induction of the lactose operon requires ________.


A) lactose present
B) lactose and glucose present
C) lactose present without glucose
D) lactose and arabinose present
E) All of the choices induce the lactose operon

F) A) and D)
G) A) and E)

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During DNA replication,synthesis of the leading strand of DNA differs from the synthesis of the lagging strand in that ________.


A) the leading strand is synthesized continuously toward the replication fork,whereas the lagging strand extends away from the fork and is synthesized in short segments called Okazaki fragments
B) the leading strand is synthesized away from the fork and is made in short segments called Okazaki fragments whereas the lagging strand extends continuously toward the replication fork
C) the leading strand is made in the 5'-3' direction by DNA polymerase III,whereas the lagging strand is synthesized in the opposite direction,3'-5'
D) only the lagging strand requires a primer for each of the Okazaki fragments; the leading strand does not require a primer to begin synthesis of the daughter strand

E) A) and D)
F) B) and C)

Correct Answer

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An RN working in a research unit is responsible for data and specimen collection for multiple research studies. A patient is admitted as a participant in a study focused on the role of tRNA mutations in Alzheimer's disease. The 78-year-old male is accompanied by his wife and daughter. Prior to obtaining the first blood specimen, the study coordinator provides education regarding the importance of the study and the overall process of protein synthesis. -Which tRNA anticodon would properly base-pair with an mRNA codon of cytosine-uracil-guanine (CUG) ?


A) GTC
B) ATC
C) GAC
D) UCA

E) All of the above
F) B) and C)

Correct Answer

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Amplification of DNA is accomplished by ________.


A) polymerase chain reaction
B) DNA sequencing
C) gene probes
D) southern blot
E) western blot

F) C) and D)
G) B) and E)

Correct Answer

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The emerging field of synthetic biology,while offering promising breakthroughs in medicine and energy production,is not without concern.  Apprehension by ethicists is understandable since ________.


A) the ability to create life from scratch raises a multitude of issues
B) medical insurance costs will likely skyrocket
C) mutations in manufactured cells will cause problems for existing organisms
D) oil and gas prices will increase as a result of the decreased demand for fossil fuels

E) C) and D)
F) A) and D)

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Common vectors used to transfer a piece of DNA into a cloning host are ________.


A) plasmids
B) viruses
C) bacteriophages
D) artificial chromosomes
E) All of the choices are correct

F) None of the above
G) A) and B)

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Induced mutations result from errors in DNA replication.

A) True
B) False

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Mastery of synthetic biology will allow humans to ________.


A) make new organisms using only chemicals as the starting materials
B) synthesize chemicals in cells that are missing due to a genetic anomaly
C) construct complex molecules in situ that will target cancerous cells in tissues
D) design alternative forms of energy production
E) All of the choices are possibilities from synthetic biology

F) B) and C)
G) C) and D)

Correct Answer

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Genomic ________ are collections of isolated genes maintained in a cloning host.


A) DNA
B) libraries
C) clones
D) digests
E) books

F) D) and E)
G) B) and C)

Correct Answer

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