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Virtually all amino acid-based hormones exert their signaling effects through intracellular___________.


A) nucleotides
B) calcium
C) deactivating ions
D) second messengers

E) All of the above
F) A) and C)

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Iodine is an essential element required for the synthesis of thyroxine.

A) True
B) False

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Melatonin ____________ .


A) is responsible for regulating the sleep cycle
B) triggers sexual maturation and puberty
C) is produced by the parathyroid glands
D) is at its highest levels at around noon

E) A) and B)
F) None of the above

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All anterior pituitary hormones EXCEPT growth hormone affect their target cells via a cyclic AMP second-messenger system.

A) True
B) False

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Enterochromaffin-like cells of the gastric mucosa can be triggered to release histamine. Histamine, in this case, causes nearby parietal cells of the stomach lining to produce hydrochloric acid. The effect of histamine on parietal cells would best be described as a(n) ____________.


A) second messenger
B) exocrine
C) paracrine
D) autocrine

E) A) and C)
F) A) and D)

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Growth hormone solely exerts its influence by targeting other endocrine glands to produce hormones.

A) True
B) False

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Glucagon and insulin both target the cells of the liver and are both made in the pancreas, yet they have very different effects on the cells they target. What accounts for this fact?

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Glucagon and insulin...

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Which of the following hormones suppresses appetite and increases energy expenditure?


A) gastrin
B) secretin
C) aldosterone
D) leptin

E) None of the above
F) B) and C)

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D

Antidiuretic hormone (ADH) ___________.


A) increases urine production
B) promotes dehydration
C) secretion is inhibited by alcohol
D) is produced by the anterior pituitary

E) None of the above
F) B) and C)

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It was often rumored that one of our deceased presidents was suffering from Addison's disease (inadequate synthesis of mineralocorticoids and glucocorticoids). What symptoms may have led to the diagnosis of this condition?

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Low body weight, low plasma gl...

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Which of the following is NOT a typical result of a long-term stress response?


A) loss of muscle mass
B) decreased production of glucocorticoids
C) impaired immune function
D) elevated blood pressure

E) B) and C)
F) C) and D)

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Enteroendocrine cells of the GI tract produce some hormones that are chemically identical to neurotransmitters.

A) True
B) False

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A person who drinks a lot of alcoholic beverages must urinate frequently. Why?

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The function of ADH is to increase water reabsorption in the kidneys, producing concentrated urine. Alcohol inhibits ADH secretion, causing copious urine output.

The major targets of growth hormone are ___________.


A) the liver and gall bladder
B) the blood vessels
C) liver, bones, and skeletal muscles
D) the thyroid and adrenal glands

E) All of the above
F) A) and D)

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Mineralocorticoid is to aldosterone as glucocorticoid is to___________ .


A) cortisol
B) testosterone
C) epinephrine
D) estrogen

E) A) and B)
F) A) and D)

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John is a 26-year-old man who begins to notice a progressive enlargement of feet, hands, cranium, nose, and lower jaw bone. His doctor recommends a pituitary gland operation. What is the most likely diagnosis? Why?

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The diagnosis is acromegaly. T...

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Which of the following is NOT a steroid-based hormone?


A) epinephrine
B) aldosterone
C) estrogen
D) cortisol

E) A) and D)
F) B) and D)

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Define synergism in hormone interaction at target cells and give an example.

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Synergism occurs when more than one horm...

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Dave has discovered a new lipid-soluble hormone. Which of the following is true regarding this hormone?


A) will likely act through a second-messenger system
B) receptor will be located on the plasma membrane
C) will be bound to a transport protein in the blood
D) can be stored in secretory vesicles

E) C) and D)
F) B) and C)

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C

Gluconeogenesis, the formation of glucose from fats and proteins, is due to the action of ___________.


A) cortisol
B) insulin
C) secretin
D) aldosterone

E) A) and B)
F) A) and C)

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