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What tissue serves as the model for bones formed during endochondral ossification?


A) hyaline cartilage
B) fibrocartilage
C) spongy bone
D) compact bone

E) A) and D)
F) B) and C)

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What do fibroblasts contribute to bone repair?


A) Fibroblasts direct the transition from primary bone to secondary bone.
B) Fibroblasts secrete hyaline cartilage to form a soft callus.
C) Fibroblasts form new collagen fibers to bridge the gap between bone fragments.
D) Fibroblasts form the hematoma that involves a mass of blood cells.

E) A) and C)
F) All of the above

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What is the first step of bone repair?


A) soft callus formation
B) bone callus formation
C) hematoma formation
D) primary bone is replaced with secondary bone

E) A) and B)
F) A) and C)

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Thin, broad bones should be classified as:


A) irregular bones.
B) flat bones.
C) short bones.
D) long bones.

E) None of the above
F) C) and D)

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In the laboratory, your professor presents a bone for study. She explains it has a diaphysis and epiphyses. Determine the type of bone, by shape, that she has presented and explain how you came to your conclusion.

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Short, flat, irregular, and sesamoid bon...

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Bone deposition exceeds bone resorption when bones are stressed through compression or tension.

A) True
B) False

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What structure allows the diaphysis of the bone to increase in length?


A) epiphyseal plate
B) epiphyseal line
C) lacunae
D) osteon

E) B) and C)
F) A) and D)

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Within the epiphyseal plate, which zone houses actively dividing cartilage cells in their lacunae?


A) zone of reserve cartilage
B) zone of proliferation
C) zone of hypertrophy
D) zone of ossification

E) None of the above
F) B) and C)

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How are carpals and tarsals classified by shape?


A) short bones
B) long bones
C) irregular bones
D) flat bones

E) B) and C)
F) A) and D)

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Relatively inactive bone cells that help to maintain the ECM are:


A) osteoblasts.
B) osteogenic cells.
C) osteocytes.
D) osteoclasts.

E) C) and D)
F) A) and B)

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Appositional growth produces:


A) growth in length.
B) intramembranous ossification.
C) endochondral ossification.
D) growth in width.

E) A) and C)
F) All of the above

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Bone is the most important storehouse in the body for minerals such as calcium, phosphorus, and magnesium salts.

A) True
B) False

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A radiograph reveals epiphyseal lines in the long bones of a 12 -year -old's hand. Which of the following statements is correct?


A) More growth will occur during the teenage years as sex hormones stimulate rebuilding of epiphyseal plates.
B) Administration of growth hormone will stimulate further bone growth in length.
C) Intramembranous ossification will enable continued growth in length.
D) The epiphyseal plates have ossified and further growth in length is not possible.

E) B) and D)
F) All of the above

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As a result of the increase of testosterone at puberty for males:


A) intramembranous ossification increases.
B) appositional bone growth increases.
C) osteoblasts increase the rate of bone resorption.
D) epiphyseal plates widen rapidly.

E) A) and B)
F) A) and C)

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What type of bone is adapted to withstand stresses arriving from many directions?


A) lamellar bone
B) compact bone
C) spongy bone
D) osteon bone

E) A) and D)
F) B) and C)

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What is NOT an effect of growth hormone?


A) Growth hormone directly stimulates osteoblasts in the periosteum to promote appositional growth.
B) Growth hormone increases the rate of mitosis in the epiphyseal plate of growing bones.
C) Growth hormone promotes the closure of the epiphyseal plate.
D) Growth hormone increases the activity of osteogenic cells.

E) A) and B)
F) A) and C)

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The predominant ingredient of the inorganic matrix is calcium salts, with the majority existing as large molecules of hydroxyapatite crystals.

A) True
B) False

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Primary ossification centers develop in long bones in the:


A) periosteum.
B) articular cartilage.
C) diaphysis.
D) epiphyses.

E) None of the above
F) B) and C)

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What is the last process to occur in the epiphyseal plate?


A) maturation
B) calcification
C) proliferation
D) ossification

E) B) and C)
F) All of the above

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Summarize the differences between intramembranous and endochondral ossification.

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There are two types of ossification-intr...

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